Retatrutide - Eli Lilly and Company
Alternative Names: GGG Tri-agonist - Eli Lilly and Company; GLP-1/GIP/glucagon tri-agonist - Eli Lilly and Company; LY-3437943Latest Information Update: 03 Apr 2026
At a glance
- Originator Eli Lilly and Company
- Developer Eli Lilly and Company; Hudson Biotech
- Class Analgesics; Antihyperglycaemics; Antirheumatics; Cardiovascular therapies; Hepatoprotectants; Obesity therapies; Peptides; Sleep disorder therapies; Urologics
- Mechanism of Action Gastric inhibitory polypeptide receptor agonists; Glucagon receptor agonists; Glucagon-like peptide-1 receptor agonists
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Back pain; Cardiovascular disorders; Non-alcoholic fatty liver disease; Obesity; Osteoarthritis; Sleep apnoea syndrome; Type 2 diabetes mellitus
- Phase II Renal failure
Most Recent Events
- 19 Mar 2026 Adverse events and efficacy data from a phase-III TRANSCEND-T2D-1 trial in Type-2 diabetes mellitus released by Eli Lilly and Company
- 20 Feb 2026 Eli Lily and Company completes a phase III trial in Type 2 diabetes mellitus in Mexico, India, Puerto Rico and the US (SC) (NCT06354660)
- 15 Feb 2026 Phase-II clinical trials in Obesity in China (SC) (NCT07467447)