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Apocynin/paeonol - AKL Research and Development

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Drug Profile

Apocynin/paeonol - AKL Research and Development

Alternative Names: AKL-4; APPA - AKL Research and Development

Latest Information Update: 28 Mar 2023

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At a glance

  • Originator AKL Research and development
  • Developer AKL Research and development; University of Liverpool
  • Class Acetophenones; Analgesics; Anti-inflammatories; Skin disorder therapies
  • Mechanism of Action NF-E2-related factor 2 modulators; NF-kappa B kinase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Osteoarthritis
  • No development reported Scleroderma

Most Recent Events

  • 28 Mar 2023 No recent reports of development identified for preclinical development in Scleroderma in United Kingdom (PO)
  • 20 Mar 2023 Pharmacodynamics data from preclinical trial in osteoarthritis released by AKL Research and development
  • 01 Jun 2022 Efficacy and safety data from a phase II trial in Osteoarthritis presented at the 23rd Annual Congress of the European League Against Rheumatism (EULAR-2022)

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