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Xaluritamig - Amgen/Xencor

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Drug Profile

Xaluritamig - Amgen/Xencor

Alternative Names: AMG-509

Latest Information Update: 03 Jan 2025

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At a glance

  • Originator Amgen; Xencor
  • Developer Amgen; BeiGene; Xencor
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Immunostimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Prostate cancer
  • Preclinical Ewing's sarcoma

Most Recent Events

  • 09 Dec 2024 Phase-III clinical trials in Prostate cancer (Hormone refractory, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT06691984)
  • 25 Nov 2024 Phase-I clinical trials in Prostate cancer (First-line therapy, Neoadjuvant therapy) in USA, Germany (IV) (NCT06613100)
  • 06 Nov 2024 Xencor plans a phase III trial for Prostate cancer (Metastatic disease) in the fourth quarter of 2024

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