Zamtocabtagene autoleucel - Miltenyi Biomedicine
Alternative Names: Anti-CD20-anti-CD19 CAR T cells; Anti-CD2019 CAR T cells; CAR-20/19-T cells - Miltenyi Biotec; CD20-CD19-targeting CAR T Cells; CD2019-targeting CAR T cells; MB-CART2019.1; zamto-celLatest Information Update: 21 May 2026
At a glance
- Originator Miltenyi Biomedicine
- Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase III Non-Hodgkin's lymphoma
- Phase II B-cell lymphoma; Diffuse large B cell lymphoma
- Phase I/II Multiple sclerosis
- Clinical Phase Unknown Malignant melanoma; Precursor cell lymphoblastic leukaemia-lymphoma
Most Recent Events
- 06 May 2026 Miltenyi Biomedicine in collaboration with National Heart, Lung, and Blood Institute and National Cancer Institute plans a phase II FRONTIER trial for Mantle cell lymphoma (Second-line therapy or greater) in September 2026 (IV, Infusion) (NCT07569965)
- 17 Dec 2025 Miltenyi Biotec GmbH plans a phase II DALY II Japan trial for Diffuse-large-B-cell-lymphoma (Second line therapy or greater) in Japan (IV, Infusion) in December 2025 (NCT07288879) (jRCT2033250384)
- 11 Dec 2025 Phase-II clinical trials in Diffuse large B cell lymphoma (Second-line therapy or greater) in Japan (IV) (NCT07288879)