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Zamtocabtagene autoleucel - Miltenyi Biomedicine

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Drug Profile

Zamtocabtagene autoleucel - Miltenyi Biomedicine

Alternative Names: Anti-CD20-anti-CD19 CAR T cells - Miltenyi Biotec; Anti-CD2019 CAR T cells; CAR-20/19-T cells - Miltenyi Biotec; CD20-CD19-targeting CAR T Cells - Miltenyi Biotec; CD2019-targeting CAR T cells; DALY II USA; MB-CART2019.1

Latest Information Update: 25 Jul 2024

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At a glance

  • Originator Miltenyi Biotec GmbH
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Non-Hodgkin's lymphoma
  • Phase II Diffuse large B cell lymphoma
  • Clinical Phase Unknown Malignant melanoma; Precursor cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 25 Jul 2024 Miltenyi Biotec GmbH plans the phase II DALY PED trial in B cell lymphoma (Second line therapy or greater, In infants, In children, In adolescents) in April 2025 (NCT06508931)
  • 28 May 2024 Miltenyi Biomedicine in collaboration with ICON completes a phase I/II trial in Non-Hodgkin's lymphoma (Second-line therapy or greater) in Germany (IV) (NCT03870945)
  • 05 May 2024 Clinical trials in Malignant melanoma (In adolescents, In children, In adults, In the elderly, Second-line therapy or greater) in Germany (IV) (NCT06508775)

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