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Zamtocabtagene autoleucel - Miltenyi Biomedicine

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Drug Profile

Zamtocabtagene autoleucel - Miltenyi Biomedicine

Alternative Names: Anti-CD20-anti-CD19 CAR T cells - Miltenyi Biotec; Anti-CD2019 CAR T cells; CAR-20/19-T cells - Miltenyi Biotec; CD20-CD19-targeting CAR T Cells - Miltenyi Biotec; CD2019-targeting CAR T cells; DALY II USA; MB-CART2019.1

Latest Information Update: 26 Jul 2023

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At a glance

  • Originator Miltenyi Biotec GmbH
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Non-Hodgkin's lymphoma
  • Phase II Diffuse large B cell lymphoma

Most Recent Events

  • 24 Jul 2023 Interim efficacy and adverse events data from a phase II DALY 2- USA trial in Diffuse large b-cell lymphoma presented at the 28th Congress of the European Haematology Association (EHA-2023)
  • 10 Dec 2022 Updated efficacy and safety data from a phase I/II trial in Non-Hodgkin's lymphoma presented at the 64th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2022)
  • 09 Jun 2022 Efficacy and adverse events data from a phase I/II trial in Non-Hodgkin's lymphoma presented at the 27th Congress of the European Haematology Association (EHA-2022)
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