Luveltamab tazevibulin - Sutro Biopharma
Alternative Names: anti-FolRa ADC STRO-002; anti-FolRalpha ADC STRO-002; FolR-alpha-ADC-Sutro-Biopharma; Luvelta; STRO-002Latest Information Update: 04 Sep 2025
At a glance
- Originator Sutro Biopharma
- Developer Gynecologic Oncology Group; Sutro Biopharma; Tasly Biopharmaceuticals
- Class Amides; Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates; Immunotoxins; Indoles
- Mechanism of Action Tubulin inhibitors
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes - Cancer
Highest Development Phases
- Suspended Acute myeloid leukaemia; Endometrial cancer; Fallopian tube cancer; Non-small cell lung cancer; Ovarian cancer; Peritoneal cancer; Solid tumours
Most Recent Events
- 24 Aug 2025 Sutro Biopharma terminates phase I/II REFRαME P1 trial in Acute myeloid leukemia (In neonates, In infants, In children, Second-line or greater therapy) in Austria, Canada, Denmark, France, Germany, Italy, Netherlands, Spain and USA (IV) (NCT06679582)
- 30 May 2025 Efficacy data from a compassionate use programm presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
- 15 Mar 2025 Updated adverse events and efficacy data from the phase II/III REFRaME-O1 trial in Ovarian cancer released by Sutro Biopharma