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Luveltamab tazevibulin - Sutro Biopharma

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Drug Profile

Luveltamab tazevibulin - Sutro Biopharma

Alternative Names: anti-FolRa ADC STRO-002; anti-FolRalpha ADC STRO-002; FolR-alpha-ADC-Sutro-Biopharma; Luvelta; STRO-002

Latest Information Update: 21 Mar 2025

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At a glance

  • Originator Sutro Biopharma
  • Developer Gynecologic Oncology Group; Sutro Biopharma; Tasly Biopharmaceuticals
  • Class Amides; Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates; Immunotoxins; Indoles
  • Mechanism of Action Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Suspended Acute myeloid leukaemia; Endometrial cancer; Fallopian tube cancer; Non-small cell lung cancer; Ovarian cancer; Peritoneal cancer; Solid tumours

Most Recent Events

  • 15 Mar 2025 Updated adverse events and efficacy data from the phase II/III REFRaME-O1 trial in Ovarian cancer released by Sutro Biopharma
  • 13 Mar 2025 Luveltamab tazevibulin - Sutro Biopharma is available for licensing in World as of 13 Mar 2025. https://www.sutrobio.com/
  • 13 Mar 2025 Suspended - Phase-I for Acute myeloid leukaemia (In children, In infants, Second-line therapy or greater) in USA (IV)

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