Research programme: HCN2 antagonists - Kings College London/Merck
Alternative Names: Hyperpolarisation activated cation channel 2 antagonists - MerckLatest Information Update: 28 Apr 2023
At a glance
- Originator Kings College London
- Developer Kings College London; Merck & Co
- Class Analgesics
- Mechanism of Action Hyperpolarisation activated cation channel antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- No development reported Neuropathic pain
Most Recent Events
- 28 Apr 2023 No recent reports of development identified for preclinical development in Neuropathic-pain in United Kingdom
- 08 Mar 2019 King’s College London and Wellcome entered into a licensing agreement with Merck for the development of HCN2 inhibitors
- 08 Mar 2019 Preclinical trials in Neuropathic pain in United Kingdom (unspecified route)