KVD 824
Alternative Names: KVD-824Latest Information Update: 06 Oct 2022
At a glance
- Originator Vantia Therapeutics
- Developer KalVista Pharmaceuticals
- Class Eye disorder therapies; Skin disorder therapies; Small molecules; Vascular disorder therapies
- Mechanism of Action Plasma kallikrein inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Hereditary angioedema
- Discontinued Diabetic macular oedema
Most Recent Events
- 04 Oct 2022 Adverse events data from the phase II KOMPLETE trial in Hereditary angioedema released by KalVista Pharmaceuticals
- 04 Oct 2022 KalVista Pharmaceuticals terminates the phase II KOMPLETE trial in Hereditary angioedema (Prevention) in Puerto Rico, United Kingdom, Macedonia, New Zealand, Italy, Hungary, Germany, France, Czech Republic, Canada, Australia, Bulgaria and USA (PO) due to observation of liver enzyme elevations in multiple patients (NCT05055258) (EudraCT2021-000136-59)
- 28 Apr 2022 No recent reports of development identified for phase-I development in Hereditary-angioedema(Prevention) in United Kingdom (PO, Capsule)