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ALMB 0166

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Drug Profile

ALMB 0166

Alternative Names: ALMB-0166; Humanised connexin-43 monoclonal antibody; Humanised gap junction 43 monoclonal antibody

Latest Information Update: 28 Jul 2025

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At a glance

  • Originator University of Texas Health Science Center at San Antonio
  • Developer AlaMab Therapeutics
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies; Neuroprotectants
  • Mechanism of Action Connexin 43 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Spinal cord injuries
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Osteoarthritis
  • Research Stroke
  • No development reported Spinal cord injuries

Most Recent Events

  • 28 Jul 2025 No recent reports of development identified for phase-I development in Spinal-cord-injuries in China (IV, Injection)
  • 28 Jul 2025 No recent reports of development identified for phase-I development in Spinal-cord-injuries(In volunteers) in Australia (IV)
  • 04 Jul 2023 ALMB 0166 is still in phase I trials for Spinal cord injuries (In volunteers) in Australia (IV) (CSPC Pharmaceutical Group pipeline, July 2023)

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