ALMB 0166
Alternative Names: ALMB-0166; Humanised connexin-43 monoclonal antibody; Humanised gap junction 43 monoclonal antibodyLatest Information Update: 24 Nov 2025
At a glance
- Originator University of Texas Health Science Center at San Antonio
- Developer AlaMab Therapeutics
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies; Neuroprotectants
- Mechanism of Action Connexin 43 inhibitors
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Orphan Drug Status
Yes - Spinal cord injuries
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Spinal cord injuries
- Preclinical Osteoarthritis
- Research Stroke
Most Recent Events
- 18 Nov 2025 AlaMab Therapeutics is still in phase I development in Spinal-cord-injuries in China (IV, Injection) (NCT05524103)
- 28 Jul 2025 No recent reports of development identified for phase-I development in Spinal-cord-injuries in China (IV, Injection)
- 28 Jul 2025 No recent reports of development identified for phase-I development in Spinal-cord-injuries(In volunteers) in Australia (IV)