Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

UNI 494

Next Previous
Drug Profile

UNI 494

Alternative Names: Nicorandil prodrug - Unicycive Therapeutics; UNI-494

Latest Information Update: 27 Aug 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Sphaera Pharma
  • Developer Unicycive Therapeutics
  • Class Esters; Small molecules; Urologics
  • Mechanism of Action KATP channel stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Delayed graft function
  • New Molecular Entity Yes
  • Available For Licensing Yes - Acute kidney injury; Kidney disorders

Highest Development Phases

  • Phase I Acute kidney injury
  • Preclinical Delayed graft function; Kidney disorders

Most Recent Events

  • 18 Aug 2025 UNI 494 is available for licensing as of 18 Aug 2025. https://ir.unicycive.com/news/detail/109/unicycive-therapeutics-granted-new-u-s-patent-for-uni-494 9448433
  • 18 Aug 2025 Unicycive Therapeutics has patent protection for UNI 494 in USA
  • 18 Aug 2025 Unicycive Therapeutics has patents pending for UNI 494 in USA, prior to August 2025

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top