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RTX 321

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Drug Profile

RTX 321

Alternative Names: RCT-aAPC; RTX-321; RTX-aAPC HPV; RTX‑aAPC (HPV+)

Latest Information Update: 11 Aug 2023

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At a glance

  • Originator Rubius Therapeutics
  • Developer Rubius Therapeutics [CEASED]
  • Class Antineoplastics; Cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Cell replacements; Natural killer cell stimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Anal cancer; Cervical cancer; Head and neck cancer

Most Recent Events

  • 31 Dec 2022 Discontinued - Phase-I for Anal cancer (Inoperable/Unresectable, Metastatic disease, Monotherapy, Recurrent, Second-line therapy or greater) in USA (IV) (Rubius Therapeutics website, December 2022)
  • 31 Dec 2022 Discontinued - Phase-I for Cervical cancer (Inoperable/Unresectable, Metastatic disease, Monotherapy, Recurrent, Second-line therapy or greater) in USA (IV) (Rubius Therapeutics website, December 2022)
  • 31 Dec 2022 Discontinued - Phase-I for Head and neck cancer (Inoperable/Unresectable, Metastatic disease, Monotherapy, Recurrent, Second-line therapy or greater) in USA (IV) (Rubius Therapeutics website, December 2022)

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