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Adrixetinib - Qurient Therapeutics

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Drug Profile

Adrixetinib - Qurient Therapeutics

Alternative Names: Axl/Mer/CSF1R triple Inhibitor; Q-702

Latest Information Update: 10 Oct 2025

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At a glance

  • Originator The Lead Discovery Center; The Max Planck Institute of Biochemistry; Vichem Chemie
  • Developer Merck & Co; Qurient Co
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Axl receptor tyrosine kinase inhibitors; Macrophage colony-stimulating factor receptor antagonists; Proto-oncogene protein c-mer inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Phase I Acute myeloid leukaemia; Haematological malignancies
  • No development reported Non-small cell lung cancer

Most Recent Events

  • 27 Aug 2025 Phase-I clinical trials in Haematological malignancies (Second-line therapy or greater) in USA (PO) (NCT06712810)
  • 22 Aug 2025 Qurient plans a phase I trial for Graft versus host disease (Treatment-experienced) in Spain (PO) in November 2025 (NCT07138196)
  • 30 May 2025 Preliminary efficacy, adverse event and pharmacokinetic data from a phase Ib/II trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)

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