Drug Profile

Research programme: HIV targeting BiKE and TriKE constructs - GT Biopharma

Alternative Names: HIV bnAb/CD16 Bi-specific Killer Engager; HIV bnAb/IL-15/CD16 Tri-specific Killer Engager

Latest Information Update: 28 May 2023

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At a glance

Originator University of Minnesota
Developer GT Biopharma
Class Antiretrovirals; Drug conjugates; Fab fragments; Recombinant fusion proteins
Mechanism of Action Antibody-dependent cell cytotoxicity

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

28 May 2023 No recent reports of development identified for preclinical development in HIV-infections in USA (Parenteral)
24 Apr 2019 Preclinical trials in HIV infections in USA (Parenteral)
07 Aug 2017 Oxis International is now called GT Biopharma

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