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Luvometinib - Shanghai Fosun Pharmaceutical

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Drug Profile

Luvometinib - Shanghai Fosun Pharmaceutical

Alternative Names: FCN-159; Fu Mai Ning

Latest Information Update: 03 Mar 2026

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At a glance

  • Originator Chongqing Fochon Pharmaceutical
  • Developer Shanghai Fosun Pharmaceutical
  • Class Aminopyridines; Aniline compounds; Antineoplastics; Benzene derivatives; Cyclopropanes; Fluorobenzenes; Iodobenzenes; Pyridazines; Small molecules; Sulfonamides; Vascular disorder therapies
  • Mechanism of Action MAP kinase kinase 1 inhibitors; MAP kinase kinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Brain disorders; Langerhans cell histiocytosis; Malignant histiocytic disorders; Plexiform neurofibroma
  • Phase III Glioma
  • No development reported Malignant melanoma

Most Recent Events

  • 13 Feb 2026 West China Second University Hospital initiates enrolment in a clinical trial for Langerhans cell histiocytosis (In neonates, In infants, In children, In adolescents, Combination therapy) in China (SC) (NCT07431060)
  • 27 Jan 2026 Clinical trials in Langerhans-cell histiocytosis (In children, In infants, In neonates, In adolescents, Treatment-naive) in China (PO) (NCT07371182)
  • 01 Jul 2025 Phase-III clinical trials in Glioma (In children) in China (PO)

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