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Luvometinib - Shanghai Fosun Pharmaceutical

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Drug Profile

Luvometinib - Shanghai Fosun Pharmaceutical

Alternative Names: FCN-159; Fu Mai Ning

Latest Information Update: 08 Sep 2026

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At a glance

  • Originator Chongqing Fochon Pharmaceutical
  • Developer Shanghai Fosun Pharmaceutical
  • Class Aminopyridines; Aniline compounds; Antineoplastics; Benzene derivatives; Cyclopropanes; Fluorobenzenes; Iodobenzenes; Pyridazines; Small molecules; Sulfonamides; Vascular disorder therapies
  • Mechanism of Action MAP kinase kinase 1 inhibitors; MAP kinase kinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Brain disorders; Langerhans cell histiocytosis; Malignant histiocytic disorders; Plexiform neurofibroma
  • Phase III Glioma
  • Phase II Non-small cell lung cancer
  • No development reported Malignant melanoma

Most Recent Events

  • 08 Sep 2026 700392982- trial initiated in KDM, dev table, intro updated, NSCLS indication added; FE completed
  • 25 Aug 2026 Registered for Langerhans-cell histiocytosis (In adolescents, In adults, Treatment-experienced) in China (PO) prior to August 2026
  • 16 Jul 2026 Beijing Tiantan Hospital plans a phase I/II trial for Neurofibromatosis 2, Acoustic neuroma and Meningioma (Combination therapy) in China in July 2026 (PO) (NCT07708285)

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