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Timdarpacept - ImmuneOnco Biopharma

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Drug Profile

Timdarpacept - ImmuneOnco Biopharma

Alternative Names: IMM-01 - ImmuneOnco Biopharma; IMM01; SIRPαFc - ImmuneOnco Biopharma

Latest Information Update: 24 Oct 2024

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At a glance

  • Originator ImmuneOnco Biopharma
  • Developer ImmuneOnco Biopharma; Institute of Hematology & Blood Diseases Hospital
  • Class Antineoplastics; Immunoglobulin fusion proteins; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD47 antigen inhibitors; Macrophage stimulants; Phagocyte stimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Chronic myelomonocytic leukaemia
  • Phase I/II Acute myeloid leukaemia; Myelodysplastic syndromes; Solid tumours

Most Recent Events

  • 18 Oct 2024 Phase-III clinical trials in Chronic myelomonocytic leukaemia (Combination therapy, First-line therapy) in China (IV) (NCT06647862)
  • 13 Jun 2024 ImmuneOnco Biopharmaceuticals plans a phase III trial for Hodgkin's disease (Second-line therapy or greater, Combination therapy) (IV, Infusion) in June 2024 (NCT06465446)
  • 31 May 2024 Efficacy and adverse event data from a phase II trial in Myelodysplastic syndrome presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)

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