Timdarpacept - ImmuneOnco Biopharma
Alternative Names: IMC-001 - ImmuneOnco Biopharma; IMM-01 - ImmuneOnco Biopharma; IMM01; SIRPαFc - ImmuneOnco BiopharmaLatest Information Update: 30 Jun 2025
At a glance
- Originator ImmuneOnco Biopharma
- Developer ImmuneOnco Biopharma; Institute of Hematology & Blood Diseases Hospital
- Class Antineoplastics; Immunoglobulin fusion proteins; Immunotherapies; Recombinant fusion proteins
- Mechanism of Action Antibody-dependent cell cytotoxicity; CD47 antigen inhibitors; Macrophage stimulants; Phagocyte stimulants; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Chronic myelomonocytic leukaemia
- Phase II Atherosclerosis
- Phase I/II Acute myeloid leukaemia; Myelodysplastic syndromes; Solid tumours
Most Recent Events
- 10 Mar 2025 Phase-II clinical trials in Atherosclerosis in China (Parenteral) (NCT06788431)
- 18 Oct 2024 Phase-III clinical trials in Chronic myelomonocytic leukaemia (Combination therapy, First-line therapy) in China (IV) (NCT06647862)
- 13 Sep 2024 Efficacy data from a phase I/II trial in solid tumors and lymphomas presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)