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MRG 004A

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Drug Profile

MRG 004A

Alternative Names: MRG-004; MRG004A

Latest Information Update: 14 Jun 2024

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At a glance

  • Originator Miracogen
  • Developer Lepu Biopharma
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 12 Jun 2024 Efficacy and adverse event data from phase I/II trial in Solid tumours presented at the American Society of Clinical Oncology (ASCO-2024)
  • 28 Mar 2024 No recent reports of development identified for phase-I development in Solid-tumours in China (IV)
  • 11 Mar 2024 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV) (NCT04843709)

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