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GFH 018

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Drug Profile

GFH 018

Alternative Names: GFH-018

Latest Information Update: 07 Mar 2024

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At a glance

  • Originator GenFleet Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Transforming growth factor beta type I receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 31 Dec 2023 Genfleet Therapeutics completes a phase-I/II trial in Solid tumours (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Australia (IV) (NCT04914286)
  • 06 Jun 2023 Efficacy and adverse events data from a phase Ib/II trial in solid tumours released by Genfleet Therapeutics
  • 02 Jun 2023 Efficacy, pharmacokinetic and adverse events data from a phase I trial in Solid tumors presented at the 59th Annual Meeting of the American Society of Clinical Oncology (ASCO-2023)

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