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Becotatug vedotin - Lepu Biopharma

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Drug Profile

Becotatug vedotin - Lepu Biopharma

Alternative Names: MEIYOUHENG; MRG-003

Latest Information Update: 24 Jul 2026

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At a glance

  • Originator Miracogen
  • Developer Lepu Biopharma; Miracogen
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Immunotherapies; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Nasopharyngeal cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Nasopharyngeal cancer
  • Phase III Squamous cell cancer
  • Phase II Biliary cancer; Gastric cancer; Non-small cell lung cancer; Thyroid cancer
  • Phase I/II Solid tumours
  • Phase I Penile cancer

Most Recent Events

  • 06 Jul 2026 Phase-II clinical trials in Squamous cell cancer (Late-stage disease, Combination therapy) in China (IV) (NCT07586124)
  • 20 May 2026 Lepu Biopharma plans a phase II trial in Squamous cell cancer (Late-stage disease, Combination therapy) in China (IV) (NCT07586124)
  • 12 Feb 2026 Phase-I clinical trials in Penile cancer (First-line therapy, Metastatic disease, Late-stage disease, Combination therapy, Inoperable/Unresectable) in China (IV) (NCT07054307)

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