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Adiponectin analogue - Allysta Pharmaceuticals

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Drug Profile

Adiponectin analogue - Allysta Pharmaceuticals

Alternative Names: Adiponectin peptide analog - Allysta Pharmaceuticals; ADP 355; ALY 688; ALY 732; ALY-688-ER; ALY-688-SR

Latest Information Update: 12 Nov 2025

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At a glance

  • Originator Allysta Pharmaceuticals
  • Class Adipokines; Anti-inflammatories; Antifibrotics; Eye disorder therapies; Hepatoprotectants; Peptides
  • Mechanism of Action Adiponectin receptor agonists; Fatty acid synthetase complex inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Duchenne muscular dystrophy; Eye disorders; Liver disorders; Pulmonary fibrosis; Scleroderma
  • Discontinued Dry eyes; Non-alcoholic steatohepatitis

Most Recent Events

  • 12 Nov 2025 Discontinued - Phase-I for Non-alcoholic steatohepatitis in Australia (SC) (Allysta Pharmaceuticals pipeline; November 2025)
  • 12 Nov 2025 Discontinued - Phase-II/III for Dry eyes in USA (Ophthalmic) (Allysta Pharmaceuticals pipeline; November 2025)
  • 12 Nov 2025 Preclinical trials in Duchenne muscular dystrophy in USA (SC) (Allysta Pharmaceuticals pipeline; November 2025)

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