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RG 6084

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Drug Profile

RG 6084

Alternative Names: PD-L1 LNA - Roche; RG-6084; RO-7191863

Latest Information Update: 05 Jun 2025

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At a glance

  • Originator Roche
  • Class Antisense oligonucleotides; Antivirals
  • Mechanism of Action B7-H1 antigen expression inhibitors; Gene silencing
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hepatitis B

Most Recent Events

  • 15 Nov 2024 Efficacy and adverse events data from a phase II trial in Hepatitis B presented at the 75th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2024)
  • 15 Nov 2024 Safety, pharmacokinetics, efficacy and pharmacodynamics data from a phase I trial in Hepatitis Bpresented at the 75th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2024)
  • 15 Nov 2024 Efficacy data from a phase II trial in Hepatitis B presented at the Liver Meeting 2024: 75th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2024)

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