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RG 6084

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Drug Profile

RG 6084

Alternative Names: PD-L1 LNA - Roche; RG-6084; RO-7191863

Latest Information Update: 08 Nov 2024

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At a glance

  • Originator Roche
  • Class Antisense oligonucleotides; Antivirals
  • Mechanism of Action B7-H1 antigen expression inhibitors; Gene silencing
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hepatitis B

Most Recent Events

  • 08 Nov 2024 Discontinued - Phase-I for Hepatitis B in Switzerland (SC)
  • 08 Nov 2024 Discontinued - Phase-II for Hepatitis B (Combination therapy, Treatment-experienced) in USA, Bulgaria, Canada, Chile, China, France, Hong Kong, New Zealand, South Korea, Spain, Taiwan, Thailand, United Kingdom, Belgium, Romania (SC)
  • 19 Jul 2024 Hoffmann-La Roche completes the Phase-II Piranga trials in Hepatitis B (Combination therapy, Treatment-experienced) in the US, Belgium, Bulgaria, Canada, Chile, China, France, Hong Kong, New Zealand, South Korea, Romania, Spain, Taiwan, Thailand and the UK (NCT04225715) (EudraCT2019-002086-35)

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