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AB 205

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Drug Profile

AB 205

Alternative Names: AB-205; AB-205 + HDT-ASCT; AB-205 + mdUCBT; AB-205-L; AB-205-S; AB-207; E-CEL UVEC cells; Engineered human umbilical vein endothelial cells – Angiocrine Bioscience; Universal E-CEL® Cell Therapy

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator Angiocrine Bioscience
  • Developer Angiocrine Bioscience; Weill Cornell Medical College
  • Class Antineoplastics; Chemoprotectants; Gene therapies; Stem cell therapies
  • Mechanism of Action Cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chemotherapy-induced damage
  • New Molecular Entity No

Highest Development Phases

  • Phase III Chemotherapy-induced damage
  • Phase I/II Gastrointestinal disorders; Leukaemia; Myelodysplastic syndromes
  • Phase I Fissure in ano
  • No development reported Rectal fistula; Shoulder injuries; Soft tissue injuries
  • Discontinued Sickle cell anaemia

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Rectal-fistula(Adjunctive treatment) in USA (IV, Injection)
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Shoulder-injuries(Adjunctive treatment) in USA (Injection)
  • 28 Jun 2025 No recent reports of development identified for research development in Soft tissue injuries in USA

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