Drug Profile

VX 814

Alternative Names: VX-814

Latest Information Update: 02 Oct 2021

Price :

$50 ^*

Note:

Adis is an information provider. We do not sell or distribute actual drugs.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

Originator Vertex Pharmaceuticals
Class Small molecules
Mechanism of Action Alpha 1-antitrypsin modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Alpha 1-antitrypsin deficiency

Most Recent Events

14 Oct 2020 Discontinued - Phase-II for Alpha 1-antitrypsin deficiency in USA, Germany, United Kingdom, Canada, Sweden, Ireland (PO)
14 Oct 2020 Adverse events and pharmacokinetics data from a phase II trial for Alpha 1-antitrypsin deficiency released by Vertex
04 May 2020 Vertex Pharmaceuticals reinitiates a phase II trial in Alpha 1-antitrypsin deficiency in USA, UK, Germany, Sweden and Canada (PO) (NCT04167345)

You need to be a logged in or subscribed to view this content Request demo

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com