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Research programme: oncolytic vaccinia virus therapies - AstraZeneca/Transgene

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Drug Profile

Research programme: oncolytic vaccinia virus therapies - AstraZeneca/Transgene

Alternative Names: engineered oncolytic vaccinia virus candidates - AstraZeneca/Transgene; Invir.IOTM based armed oncolytic immunotherapies; oncolytic virus immunotherapies - AstraZeneca/Transgene

Latest Information Update: 28 Apr 2025

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At a glance

  • Originator Transgene
  • Class Antineoplastics; Gene therapies; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Cell death stimulants; Immunologic cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 28 Apr 2025 No recent reports of development identified for preclinical development in Cancer in France (Parenteral)
  • 05 May 2023 AstraZeneca terminates collaboration agreement with Transgene for co-development of engineered oncolytic vaccinia virus for Cancer
  • 15 Dec 2021 AstraZeneca exercises license option from Transgene for an undisclosed oncolytic virus

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