Anti-EGFRvIII-directed CAR T-cell therapy - Shenzhen BinDeBio
Latest Information Update: 21 May 2019
At a glance
- Originator Shenzhen BinDeBio
- Developer Henan Provincial Hospital; Shenzhen BinDeBio
- Class CAR-T cell therapies; Gene therapies; Immunotherapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II Glioblastoma; Liver cancer
Most Recent Events
- 15 May 2019 Phase-I/II clinical trials in Glioblastoma (Late-stage disease, Recurrent, Second-line therapy or greater) in China (IV) (NCT03941626)
- 15 May 2019 Phase-I/II clinical trials in Liver cancer (Inoperable/Unresectable, Recurrent, Second-line therapy or greater) in China (IV) (NCT03941626)
- 01 May 2019 Preclinical trials in Liver cancer and Glioblastoma in China (IV) (NCT03941626) before May 2019