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mRNA 3745

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Drug Profile

mRNA 3745

Alternative Names: mRNA-3745

Latest Information Update: 31 Dec 2025

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At a glance

  • Originator Moderna Therapeutics
  • Class RNA
  • Mechanism of Action Glucose 6 phosphatase expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glycogen storage disease type I
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Glycogen storage disease type I

Most Recent Events

  • 20 Nov 2025 Discontinued - Phase-I/II for Glycogen storage disease type I (In adolescents, In children, In the elderly, In adults) in Canada (IV) due to strategic prioritization
  • 20 Nov 2025 Discontinued - Phase-I/II for Glycogen storage disease type I (In adolescents, In children, In the elderly, In adults) in USA (IV) due to strategic prioritization
  • 28 Feb 2024 mRNA 3745 receives Orphan Drug status for Glycogen storage disease type I in European Union prior to February 2024

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