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Baxdrostat - CinCor Pharma

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Drug Profile

Baxdrostat - CinCor Pharma

Alternative Names: CIN-107

Latest Information Update: 09 Feb 2026

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At a glance

  • Originator Roche
  • Developer AstraZeneca; CinCor Pharma; CinRx Pharma
  • Class Amides; Antihypertensives; Antisecretories; Isoquinolines; Small molecules
  • Mechanism of Action Cytochrome P-450 CYP11B2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Hypertension
  • Phase III Hyperaldosteronism; Renal failure
  • Phase II Kidney disorders
  • No development reported Spinal cord disorders

Most Recent Events

  • 05 Dec 2025 Phase-II clinical trials in Hypertension in Canada, Taiwan, Ukraine, United Kingdom (PO) (NCT07222917)
  • 05 Dec 2025 Phase-II clinical trials in Kidney disorders in USA, Canada, Taiwan, Ukraine, United Kingdom (PO) (NCT07222917)
  • 05 Dec 2025 AstraZeneca initiates phase-II BaxDuo-Baltic clinical trial in Hypertension in Canada, Taiwan, Ukraine, United Kingdom (PO) (NCT07222917)

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