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Baxdrostat - CinCor Pharma

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Drug Profile

Baxdrostat - CinCor Pharma

Alternative Names: CIN-107

Latest Information Update: 26 Dec 2024

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At a glance

  • Originator Roche
  • Developer AstraZeneca; CinCor Pharma; CinRx Pharma
  • Class Amides; Antihypertensives; Antisecretories; Isoquinolines; Small molecules
  • Mechanism of Action Aldosterone synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Hypertension; Renal failure
  • Phase II Hyperaldosteronism
  • No development reported Spinal cord disorders

Most Recent Events

  • 19 Dec 2024 AstraZeneca plans a phase III trial in Hypertension and Kidney disorders (Combination therapy) in USA (PO, Tablets) in March 2025(NCT06742723)
  • 06 Nov 2024 AstraZeneca plans the phase III Prevent-HF trial in Heart failure (Combination-therapy, Prevention) in Argentina, Australia, Bulgaria, Canada, Germany, Greece, Italy, Malaysia, Netherlands, Philippines, South Africa, Thailand (PO, Tablet), in March 2025 (NCT06677060)
  • 01 Nov 2024 AstraZeneca initiates a phase I pharmacokinetic trial (In volunteers) in USA (PO) (NCT06657105)

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