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Baxdrostat - CinCor Pharma

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Drug Profile

Baxdrostat - CinCor Pharma

Alternative Names: CIN-107

Latest Information Update: 08 Dec 2025

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At a glance

  • Originator Roche
  • Developer AstraZeneca; CinCor Pharma; CinRx Pharma
  • Class Amides; Antihypertensives; Antisecretories; Isoquinolines; Small molecules
  • Mechanism of Action Cytochrome P-450 CYP11B2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Hypertension
  • Phase III Hyperaldosteronism; Renal failure
  • No development reported Spinal cord disorders

Most Recent Events

  • 02 Dec 2025 Preregistration for Hypertension (Adjunctive treatment) in USA (PO)
  • 02 Dec 2025 AstraZeneca anticipates PDUFA date for NDA application of Baxdrostat in Hypertension in USA in 2Q of 2026
  • 02 Dec 2025 US FDA accepts NDA for Baxdrostat for Hypertension (Adjunctive treatment) for priority review

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