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Baxdrostat - CinCor Pharma

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Drug Profile

Baxdrostat - CinCor Pharma

Alternative Names: CIN-107

Latest Information Update: 11 Jun 2025

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At a glance

  • Originator Roche
  • Developer AstraZeneca; CinCor Pharma; CinRx Pharma
  • Class Amides; Antihypertensives; Antisecretories; Isoquinolines; Small molecules
  • Mechanism of Action Aldosterone synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Hypertension; Renal failure
  • Phase II Hyperaldosteronism
  • No development reported Spinal cord disorders

Most Recent Events

  • 06 Jun 2025 AstraZeneca plans a phase III trial for Hyperaldosteronism in Canada, Germany, Italy, Spain, United Kingdom (PO) (NCT07007793)
  • 14 Mar 2025 Phase-III clinical trials in Renal failure (Combination therapy, Prevention) in Vietnam, Ukraine, United Kingdom, Turkey, Thailand, Taiwan, Sweden, South Africa, Spain, Slovakia, Romania, Poland, Philippines, Peru, Netherlands, Mexico, Mexico, Malaysia, Japan, Italy, Israel, India, Hungary, Germany, Greece, France, Denmark, Czech Republic, China, Bulgaria, Brazil, Australia, Argentina, USA (PO) (NCT06677060) (EudraCT2024-514506-32-00)
  • 03 Mar 2025 Phase-III clinical trials in Hypertension in United Kingdom, Ukraine, Thailand, Taiwan, Singapore, China, Canada, Argentina, Australia, USA (PO) (NCT06742723)

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