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KPG 818

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Drug Profile

KPG 818

Alternative Names: KPG-818; KPG-818 capsules

Latest Information Update: 07 Mar 2025

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At a glance

  • Originator Kangpu Biopharmaceuticals
  • Class Anti-inflammatories; Antineoplastics; Small molecules
  • Mechanism of Action CRBN protein modulators; Ubiquitin protein ligase complex modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Inflammatory bowel diseases
  • Phase I/II Systemic lupus erythematosus
  • Phase I Haematological malignancies
  • Preclinical Behcet's syndrome; Crohn's disease; Multiple myeloma

Most Recent Events

  • 25 Feb 2025 Preclinical trials in Multiple myeloma in China (PO) before February 2025
  • 25 Feb 2025 CDE of China National Medical Products Administration approves IND of KPG 818 in Multiple myeloma
  • 20 Sep 2024 Adverse events and pharmacokinetics data from a phase I trial in Systemic lupus erythematosus (In volunteers) released by Kangpu Biopharmaceuticals

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