Drug Profile

CRS 0540

Alternative Names: CRS-0540

Latest Information Update: 28 May 2023

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At a glance

Originator Crestone
Class Antibacterials; Small molecules; Thiadiazoles; Urea compounds
Mechanism of Action DNA-directed DNA polymerase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

No development reported Gram-positive infections

Most Recent Events

28 May 2023 No recent reports of development identified for preclinical development in Gram-positive-infections in USA (PO)
09 Jun 2022 Preclinical pharmacodynamic and antimicrobial data in gram positive infections presented at the ASM Microbe 2022 (ASM Microbe-2022)
01 Jul 2020 Crestone plans a phase I trial in Gram-positive infections

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