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AB 2004

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Drug Profile

AB 2004

Alternative Names: AB-2004

Latest Information Update: 25 Nov 2025

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At a glance

  • Originator California Institute of Technology/CalTech
  • Developer Vertero Therapeutics
  • Class Behavioural disorder therapies; Neuroprotectants; Small molecules
  • Mechanism of Action Microbiome modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Autism spectrum disorder

Most Recent Events

  • 15 Dec 2023 Vertero Therapeutics completes phase-II clinical trials in Autism spectrum disorder (In adolescents, In children) in New Zealand, US and Australia (PO) (NCT04895215)
  • 26 Sep 2023 Axial Therapeutics completes enrolment in its phase IIb trial for Autism spectrum disorder in United States, Australia and New Zealand
  • 05 Apr 2022 Updated pharmacodynamics data from preclinical studies in Autism spectrum disorder released by Axial Therapeutics

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