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si 544

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Drug Profile

si 544

Alternative Names: si-544

Latest Information Update: 16 Jan 2024

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At a glance

  • Originator selectION
  • Class Antineoplastics; Immunotherapies; Peptides; Skin disorder therapies
  • Mechanism of Action Kv1.3 potassium channel inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Atopic dermatitis; Psoriasis; Psoriatic arthritis
  • Preclinical Cutaneous T-cell lymphoma; Rheumatoid arthritis
  • No development reported Autoimmune disorders; Transplant rejection

Most Recent Events

  • 16 Jan 2024 si 544 is in preclinical development in Cutaneous-T-cell-lymphoma in Germany and USA (selectION pipeline, January 2024)
  • 16 Jan 2024 Preclinical trials in Rheumatoid arthritis in Germany (unspecified route) (selectION pipeline, January 2024)
  • 11 Jan 2024 Phase-I clinical trials in Psoriasis in Germany (SC) (NCT06191042) (EudraCT2023-507393-40)

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