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BIIB 100

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Drug Profile

BIIB 100

Alternative Names: BIIB-100; KPT 350

Latest Information Update: 08 Jul 2025

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At a glance

  • Originator Karyopharm Therapeutics
  • Class Anti-inflammatories; Antiepileptic drugs; Antineoplastics; Antirheumatics; Fluorinated hydrocarbons; Hydrazines; Neuroprotectants; Small molecules; Triazoles
  • Mechanism of Action Exportin 1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Amyotrophic lateral sclerosis

Highest Development Phases

  • Phase I Amyotrophic lateral sclerosis
  • Preclinical Unspecified; Uveal melanoma
  • Discontinued Brain injuries; Duchenne muscular dystrophy; Epilepsy; Multiple sclerosis; Rheumatoid arthritis; Systemic lupus erythematosus

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Uveal melanoma presented at the 116th Annual Meeting of the American Association for Cancer Research 2025 (AACR-2025)
  • 04 Apr 2025 Preclinical trials in Uveal melanoma in USA (PO), prior to April 2025
  • 31 Dec 2024 Preclinical trials in Unspecified in USA (PO)

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