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Drug Profile

LY 3526318

Alternative Names: LY-3526318; LY356318; TRPA1 Antagonist I - Eli Lilly

Latest Information Update: 24 Jan 2023

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At a glance

  • Originator Eli Lilly and Company
  • Class Analgesics; Non-opioid analgesics; Small molecules
  • Mechanism of Action TRPA1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Neuropathic pain; Pain

Most Recent Events

  • 09 Jan 2023 Eli Lilly and Company withdraws a phase I trial prior to enrolment in Healthy volunteers in Japan (PO) due to a business decision (NCT05580250)
  • 14 Oct 2022 Eli Lilly and Company plans a phase I safety and pharmacokinetics trial in healthy volunteers in Japan (PO) (NCT05580250)
  • 13 Oct 2022 Eli Lilly and Company completes a phase II trial in Neuropathic pain in USA and Puerto Rico (PO) (NCT05177094)

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