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Resomelagon - Synact Pharma

Drug Profile

Resomelagon - Synact Pharma

Alternative Names: AP-1189

Latest Information Update: 15 Apr 2025

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At a glance

  • Originator Synact Pharma
  • Class Anti-inflammatories; Antirheumatics; Hydrazines; Nitro compounds; Pyrroles; Small molecules
  • Mechanism of Action Melanocortin type 1 receptor agonists; Melanocortin type 3 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Membranous glomerulonephritis; Rheumatoid arthritis; SARS-CoV-2 acute respiratory disease
  • No development reported Inflammation

Most Recent Events

  • 08 Apr 2025 Federal University of Minas Gerais plans the phase IIa RESOVIR-2 trial for Dengue in Brazil (PO), in April 2025 (NCT06917001)
  • 14 Nov 2024 Efficacy and adverse events data from a phase II EXPAND trial in rheumatoid arthritis presented at the American College of Rheumatology Convergence (ACR-2024)
  • 01 Oct 2024 Phase-II clinical trials in Rheumatoid arthritis (Combination therapy, Treatment-naive) in USA (PO) (NCT06671054)

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