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OST 503

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Drug Profile

OST 503

Alternative Names: A-503; ADXS-503; Lm immunotherapy; OST-503

Latest Information Update: 16 May 2025

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At a glance

  • Originator Advaxis
  • Developer Ayala Pharmaceuticals
  • Class Antineoplastics; Bacteria; Gene therapies; Immunotherapies
  • Mechanism of Action Bacteria replacements; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Non-small cell lung cancer

Most Recent Events

  • 07 May 2025 OS Therapies has patent protection for Listeria monocytogenes (LM) immunotherapy platform in the US
  • 30 Jan 2025 OS Therapies acquires ADXS 503 from Ayala Pharmaceuticals
  • 19 Jan 2023 Advaxis has merged with Ayala Pharmaceuticals to form Ayala Pharmaceuticals

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