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Inaticabtagene autoleucel - Juventas Cell Therapy/CASI Pharmaceuticals

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Drug Profile

Inaticabtagene autoleucel - Juventas Cell Therapy/CASI Pharmaceuticals

Alternative Names: Anti-CD19 CAR-T cell therapy - Juventas Cell Therapy; CNCT-19; HI19α-4-1BB-ζ CAR

Latest Information Update: 20 Sep 2024

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At a glance

  • Originator Chinese Academy of Medical Sciences
  • Developer CASI Pharmaceuticals; Juventas Cell Therapy
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Precursor B-cell lymphoblastic leukaemia-lymphoma
  • New Molecular Entity No

Highest Development Phases

  • Registered Precursor B-cell lymphoblastic leukaemia-lymphoma
  • Phase II Non-Hodgkin's lymphoma
  • Phase I/II Diffuse large B cell lymphoma
  • No development reported B-cell lymphoma

Most Recent Events

  • 13 Jun 2024 Efficacy and adverse event data from the phase I trial in Non-Hodgkin lymphoma presented at the 29th Congress of the European Haematology Association 2024 (EHA-2024)
  • 20 Dec 2023 Phase-I clinical trials in Precursor B-cell lymphoblastic leukaemia-lymphoma (In children, In neonates, In infants) (IV) before December 2023 (CASI Pharmaceuticals pipeline, December 2023)
  • 08 Nov 2023 Registered for Precursor B-cell lymphoblastic leukaemia-lymphoma (Second-line therapy or greater, In adults) in China (IV)

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