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TRV 045

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Drug Profile

TRV 045

Alternative Names: TRV-045

Latest Information Update: 28 Apr 2025

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At a glance

  • Originator Trevena
  • Developer National Institutes of Health (USA); Trevena
  • Class Antiepileptic drugs; Non-opioid analgesics
  • Mechanism of Action Sphingosine 1 phosphate receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - CNS disorders; Neuropathic pain

Highest Development Phases

  • Phase I CNS disorders; Epilepsy; Pain
  • Preclinical Neuropathic pain
  • No development reported Diabetic neuropathies

Most Recent Events

  • 28 Apr 2025 No recent reports of development identified for phase-I development in Diabetic-neuropathies in USA (PO)
  • 20 Jun 2024 Pharmacodynamics data from a preclinical trial in Epilepsy released by Trevena
  • 20 Jun 2024 Pharmacodynamics data from a preclinical trial in Neuropathic pain released by Trevena

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