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Palverafusp alfa - ImmuneOnco Biopharma

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Drug Profile

Palverafusp alfa - ImmuneOnco Biopharma

Alternative Names: AXN-2510; IMM-2510; SYN-2510

Latest Information Update: 29 Sep 2025

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At a glance

  • Originator ImmuneOnco Biopharma
  • Developer Axion Bio; ImmuneOnco Biopharma; Instil Bio
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Programmed cell death-1 ligand-1 inhibitors; T lymphocyte stimulants; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Non-small cell lung cancer; Solid tumours; Triple negative breast cancer
  • Discontinued Soft tissue sarcoma

Most Recent Events

  • 29 Sep 2025 Discontinued - Phase-I for Soft tissue sarcoma (Late-stage disease, Monotherapy, Second-line therapy or greater) in China (IV) (NCT059724600) (ImmuneOnco Biopharma pipeline; September 2025)
  • 28 Sep 2025 No recent reports of development identified for phase-I development in Soft tissue sarcoma(Late-stage disease, Monotherapy, Second-line therapy or greater) in China (IV, Infusion)
  • 15 Sep 2025 Phase-I clinical trials in Solid tumours (Monotherapy, Metastatic disease, Late-stage disease) in USA (IV) (NCT07159828)

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