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Palverafusp alfa - ImmuneOnco Biopharma

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Drug Profile

Palverafusp alfa - ImmuneOnco Biopharma

Alternative Names: AXN-2510; IMM-2510; IMM-2510S; SYN-2510

Latest Information Update: 08 Oct 2026

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At a glance

  • Originator ImmuneOnco Biopharma
  • Developer Axion Bio; ImmuneOnco Biopharma; Instil Bio
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Antibody-dependent cell cytotoxicity; B7-H1 antigen inhibitors; T lymphocyte stimulants; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Liver cancer
  • Phase I/II Non-small cell lung cancer; Solid tumours; Triple negative breast cancer
  • Discontinued Soft tissue sarcoma

Most Recent Events

  • 27 Aug 2026 Phase-II clinical trials in Liver cancer (Late-stage disease, First-line therapy, Combination therapy) (IV)
  • 27 Aug 2026 Efficacy and adverse events data from a phase I trial in Solid tumours released by ImmuneOnco Biopharma
  • 21 Jul 2026 Phase-I clinical trials in Solid tumours (Late-stage disease) (SC) (ImmuneOnco Biopharmaceuticals pipeline, October 2026)

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