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HA121 28

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Drug Profile

HA121 28

Alternative Names: HA-121-28

Latest Information Update: 15 Feb 2023

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At a glance

  • Originator CSPC ZhongQi Pharmaceutical Technology
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Epidermal growth factor receptor antagonists; Proto-oncogene protein c-ret inhibitors; Vascular endothelial growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Biliary cancer; Non-small cell lung cancer; Thyroid cancer
  • Phase I Solid tumours

Most Recent Events

  • 02 Feb 2023 CSPC ZhongQi Pharmaceutical Technology terminates a phase II trial in Biliary cancer (In adults, In the elderly, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO) as primary endpoint not meeting expectations(NCT04784520)
  • 03 Mar 2022 CSPC ZhongQi Pharmaceutical Technology completes a phase I trial in Healthy volunteers in China (PO) (NCT05072535)
  • 18 Feb 2022 Phase-II clinical trials in Non-small cell lung cancer (Late-stage disease, Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater) in China (PO) (NCT05117658)

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