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AQ 280

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Drug Profile

AQ 280

Alternative Names: AQ-280; LEO-142397; Regulus

Latest Information Update: 22 Jul 2025

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At a glance

  • Originator LEO Pharma
  • Developer Aqilion
  • Class Anti-inflammatories; Small molecules
  • Mechanism of Action Janus kinase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Eosinophilic oesophagitis

Most Recent Events

  • 18 Jul 2025 Aqilion completes the phase I ARIA-2 trial for Eosinophilic Esophagitis (In volunteers) in the US (PO, Tablet)
  • 18 Jul 2025 Aqilion plans a phase IIb trial for Eosinophilic oesophagitis in the US, Canada, and Europe
  • 30 Jun 2025 Phase-I clinical trials in Eosinophilic oesophagitis (In volunteers) in USA (PO), prior to June 2025

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