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AQ 280

Drug Profile

AQ 280

Alternative Names: AQ-280; LEO-142397; Regulus

Latest Information Update: 28 May 2025

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At a glance

  • Originator LEO Pharma
  • Developer Aqilion
  • Class Anti-inflammatories; Small molecules
  • Mechanism of Action Janus kinase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Eosinophilic oesophagitis

Most Recent Events

  • 16 May 2025 Aqilion announces intention to submit IND for phase II trial in Eosinophilic oesophagitis US, Canada and Europe
  • 16 May 2025 US FDA approves IND application for AQ 280 in Eosinophilic oesophagitis
  • 12 May 2025 Aqilion plans a clinical trial for Eosinophilic oesophagitis (In volunteers) in USA (PO, Tablet) in June 2025

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