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Estradiol/progesterone intravaginal ring - Dare Bioscience

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Drug Profile

Estradiol/progesterone intravaginal ring - Dare Bioscience

Alternative Names: DARE-HRT1; JNP 0201; RECLAIM™

Latest Information Update: 27 Nov 2025

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At a glance

  • Originator Juniper Pharmaceuticals
  • Developer Catalent
  • Class Contraceptives; Estradiol congeners; Estrenes; Gonadal steroid hormones; Hormonal contraceptives; Hormonal replacements; Pregnenediones; Small molecules
  • Mechanism of Action Estrogen receptor agonists; Progesterone receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Menopausal syndrome

Most Recent Events

  • 14 Nov 2025 Dare Bioscience plans to make Estradiol/progesterone intravaginal ring available by prescription in early 2027 through a 503B compounding pathway
  • 05 Apr 2024 Dare Bioscience has patents pending for estradiol/progesterone in USA
  • 21 Jun 2023 Updated pharmacokinetics and safety data from a phase I/II trial in Menopausal syndrome released by Dare Bioscience

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