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SNT 5505

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Drug Profile

SNT 5505

Alternative Names: PXS-5505A; PXS‐5505; SLT-5505; SNT-5505

Latest Information Update: 15 Sep 2025

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At a glance

  • Originator Pharmaxis
  • Developer Syntara Limited; University of Rochester
  • Class Amines; Antifibrotics; Antineoplastics; Fluorinated hydrocarbons; Quinolones; Small molecules; Sulfones
  • Mechanism of Action Protein lysine 6 oxidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Myelofibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Liver cancer; Myelodysplastic syndromes; Myelofibrosis; Myeloid leukaemia
  • No development reported Fibrosis; Pancreatic cancer

Most Recent Events

  • 02 Sep 2025 Phase-I/II clinical trials in Myelodysplastic syndromes in Germany (PO) (CTIS2024-517237-40-00) (EudraCT-2024-517237-40-00)
  • 02 Sep 2025 Phase-I/II clinical trials in Myeloid leukaemia in Germany (PO) (CTIS2024-517237-40-00) (EudraCT-2024-517237-40-00)
  • 10 Dec 2024 Updated efficacy and adverse event data from a phase Ic/IIa trial in Myelofibrosis released by Syntara

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