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SNT 5505

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Drug Profile

SNT 5505

Alternative Names: PXS-5505A; PXS‐5505; SLT-5505; SNT-5505

Latest Information Update: 16 Dec 2024

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At a glance

  • Originator Pharmaxis
  • Developer Syntara Limited; University of Rochester
  • Class Amines; Antifibrotics; Antineoplastics; Fluorinated hydrocarbons; Quinolones; Small molecules; Sulfones
  • Mechanism of Action Protein lysine 6 oxidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Myelofibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Liver cancer; Myelofibrosis
  • Preclinical Myelodysplastic syndromes
  • No development reported Fibrosis; Pancreatic cancer

Most Recent Events

  • 10 Dec 2024 Updated efficacy and adverse event data from a phase Ic/IIa trial in Myelofibrosis released by Syntara
  • 09 Dec 2023 Pharmacodynamics, efficacy and adverse events data from a phase I/II trial in Myelofibrosis presented at the 65th American Society of Hematology Annual Meeting and Exposition (ASH-2023)
  • 04 Dec 2023 Pharmaxis is now called Syntara Limited

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