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Imdusiran - Arbutus Biopharma

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Drug Profile

Imdusiran - Arbutus Biopharma

Alternative Names: AB-729; ARB 270729

Latest Information Update: 28 Jul 2025

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At a glance

  • Originator Arbutus Biopharma
  • Developer Antios Therapeutics; Arbutus Biopharma; Assembly Biosciences
  • Class Amides; Amino sugars; Antivirals; Drug conjugates; Small interfering RNA
  • Mechanism of Action Hepatitis B surface antigen expression inhibitors; Hepatitis B virus replication inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Hepatitis B

Highest Development Phases

  • Phase II Hepatitis B; Hepatitis D

Most Recent Events

  • 28 Jul 2025 No recent reports of development identified for clinical-Phase-Unknown development in Hepatitis-B in Unknown (SC)
  • 25 Jun 2025 Imdusiran is no longer licensed to Qilu Pharmaceuticals in Greater China
  • 07 May 2025 Updated efficacy data from the phase IIa IM-PROVE II trial in Hepatitis B released by Arbutus Biopharma

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