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Drug Profile

Imdusiran - Arbutus Biopharma

Alternative Names: AB-729; ARB 270729

Latest Information Update: 25 Nov 2024

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At a glance

  • Originator Arbutus Biopharma
  • Developer Antios Therapeutics; Arbutus Biopharma; Assembly Biosciences
  • Class Amides; Amino sugars; Antivirals; Drug conjugates; Small interfering RNA
  • Mechanism of Action Hepatitis B surface antigen expression inhibitors; Hepatitis B virus replication inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Hepatitis B

Highest Development Phases

  • Phase II Hepatitis B; Hepatitis D

Most Recent Events

  • 15 Nov 2024 Updated efficacy and adverse events data from a phase IIa IM-PROVE I trial for Hepatitis B released by Arbutus Biopharma
  • 15 Nov 2024 Updated efficacy, adverse events and immunogenicity data from the phase-IIa IM-PROVE II trial in Hepatitis B released by Arbutus Biopharma
  • 15 Oct 2024 Efficacy data from the phase II IM-PROVE I trial in Hepatitis B released by Arbutus Biopharma

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