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IMSA 101

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Drug Profile

IMSA 101

Alternative Names: GB-492; IMSA-101

Latest Information Update: 04 Nov 2025

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At a glance

  • Originator ImmuneSensor
  • Developer Genor Biopharma; ImmuneSensor
  • Class Antineoplastics; Small molecules
  • Mechanism of Action STING1 protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer; Renal cell carcinoma
  • Phase I/II Solid tumours

Most Recent Events

  • 30 Jun 2025 Genor plans clinical trial in solid tumours (Combination Therapy) (Intratumoural)
  • 01 Apr 2025 ImmuneSensor Therapeutics initiates a phase II SPARK trial for Renal cell carcinoma (Metastatic disease, Combination therapy) in USA (Intratumoural, Injection) (NCT06601296)
  • 09 Dec 2024 ImmuneSensor Therapeutics terminates a phase II trial for Solid tumors (Second-line therapy or greater, Combination therapy, Metastatic disease, Late-stage disease) in the US, due to the change in ImmuneSensor corporate strategy (NCT05846659)

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